Some oral antihistamines, like Allegra (fexofenadine), Benadryl (diphenhydramine), Chlor-Trimeton (chlorpheniramine), Claritin (loratadine), and Zyrtec (cetirizine) appear to be safe after the first trimester, safe meaning they have caused no known harm in studies that have been done.
Is Zyrtec safe to take during pregnancy?
Many allergy drugs may be fine to keep taking during pregnancy, but have the discussion so you can have peace of mind. Oral antihistamines, like cetirizine (Zyrtec), chlorpheniramine (Chlor-Trimeton), diphenhydramine (Benadryl), fexofenadine (Allegra), and loratadine (Claritin) seem to be safe.
Can Zyrtec cause miscarriage?
Can taking cetirizine in pregnancy cause miscarriage? The likelihood of miscarriage has been assessed in around 430 women taking cetirizine in early pregnancy. Although the studies do not raise concern that cetirizine causes miscarriage, ongoing research is ideally required to confirm this.
Does Zyrtec cause birth defects?
Cetirizine is unlikely to cause other pregnancy complications. Studies on a small number of pregnancies did not find a higher chance for birth defects, preterm delivery (having the baby before 37 weeks), or low birth weight.
Which antihistamine is safe in first trimester?
 Preferably all drug usage including antihistamines should be deferred in the first trimester. If antihistamines have to be prescribed then first generation agents should be preferred and among them chlorpheniramine, dexchlorpheniramine and hydroxyzine should be the first choice of agents.
What category is Zyrtec for pregnancy?
Safety of Over-the-Counter Antihistamines, Decongestants, and Expectorants in Pregnancy
|Medication||Drug class||Pregnancy risk category*|
|Cetirizine (Zyrtec)||Second-generation (selective, nonsedating) antihistamine||B|
|Loratadine (Claritin)||Second-generation (selective, nonsedating) antihistamine||B|
Can allergies cause a miscarriage?
Allergic diseases cause a reduction in the quality of life due to chronic clinical signs, changing lifestyle, eating habits, and the use of drugs. They have been shown to affect fertility by means of delayed conception and an increased risk of miscarriage, or disturbed menstrual function .
Does Zyrtec affect implantation?
The Web: According to reports on the web, when you’re trying to conceive, these allergy-inhibitors — think Benadryl, Zyrtec, and Claritin, for example — may also have a negative effect on the egg’s attempt to implant in the uterus because they, in essence, block the action of the chemical called histamine, which …
Do antihistamines affect pregnancy?
Scientific research suggests that using most types of antihistamines during pregnancy is not linked to birth defects. Out of 54 studies examined, 9 studies showed potential links between certain antihistamines and certain birth defects.
What is category B in pregnancy?
Category B drugs include prenatal vitamins, acetaminophen and several other medications used routinely and safely during pregnancy. If there is a clinical need for a Category B drug, it is considered safe to use it.
Is Benadryl safe in the first trimester?
Potential harm to baby
However, several recent medical studies have found that diphenhydramine doesn’t cause these or any abnormalities at birth at all. This research shows that taking Benadryl at any stage of your pregnancy, even the first trimester, is safe.
What allergy medicine is safe while pregnant?
Many allergy medications really aren’t safe to take during pregnancy. But loratadine (found in Claritin®) and cetirizine (found in Zyrtec® and Alleroff®) are two over-the-counter (OTC) antihistamine medications that doctors consider as being safe to use during pregnancy and while breastfeeding, Dr. Zanotti says.
What birth defects can antihistamines cause?
Possible Associations Between Antihistamines and Birth Defects. Diphenhydramine (Benadryl): Cleft lip and cleft palate, neural tube defects, spina bifida, limb reduction defects, gastroschisis.