Metronidazole is used to treat genitourinary infections and is one of the most commonly used drugs in pregnancy, but it is widely thought to be relatively contraindicated in the first trimester because of a possible increased risk for birth defects.
Can I take metronidazole in early pregnancy?
Metronidazole is not used in early pregnancy because of potential adverse effects on the fetus. Metronidazole is excreted in breast milk. Females who are nursing, because of potential adverse effects on the newborn, should not use metronidazole.
Can metronidazole cause miscarriage in early pregnancy?
Miscarriage can occur in any pregnancy. It is unlikely that metronidazole would greatly increase the chance of a miscarriage. There is one large study that looked at over 4000 pregnancies with exposure to metronidazole early in pregnancy that did not find an increased chance for miscarriage.
Why is metronidazole not safe during first trimester?
Metronidazole is an FDA Pregnancy Category B drug, meaning that animal studies have not revealed evidence of harm to the fetus but that adequate, well-controlled studies among pregnant women have not been conducted. It is mutagenic in bacteria (14) and was carcinogenic in rats that consumed daily dietary doses (25).
Which antibiotic is safe in first trimester of pregnancy?
Here’s a sampling of antibiotics generally considered safe during pregnancy: Penicillins, including amoxicillin (Amoxil, Larotid) and ampicillin. Cephalosporins, including cefaclor and cephalexin (Keflex)
Can metronidazole destroy pregnancy?
Many classes of common antibiotics, such as macrolides, quinolones, tetracyclines, sulfonamides and metronidazole, were associated with an increased risk of miscarriage in early pregnancy, according to a new study.
Can I clean my womb with Flagyl to fall pregnant?
Flagyl is an antibiotic and is used to treat infections. Unless you have an infection there would be no point in taking it. You were pregnant in September, even though you lost the pregnancy. It does mean that there isn’t a problem preventing you from conceiving.
What medications are unsafe during pregnancy?
What medicines should you avoid during pregnancy?
- Bismuth subsalicylate (such as Pepto-Bismol).
- Phenylephrine or pseudoephedrine, which are decongestants. …
- Cough and cold medicines that contain guaifenesin. …
- Pain medicines like aspirin and ibuprofen (such as Advil and Motrin) and naproxen (such as Aleve).
Is it safe to treat BV in first trimester?
BV is treated with antibiotics. Antibiotics are medicines that kill infections caused by bacteria. The antibiotic may be oral (taken by mouth) or a cream or gel that you put into your vagina. Treatment with antibiotics for BV is safe for your baby during pregnancy, and it may help reduce your risk for STIs.
Can metronidazole cause birth defects?
No increased chance of birth defects overall was shown in seven of eight large studies of children exposed to metronidazole in the womb.